Cargando…

Not5-dependent co-translational assembly of Ada2 and Spt20 is essential for functional integrity of SAGA

Acetylation of histones regulates gene expression in eukaryotes. In the yeast Saccharomyces cerevisiae it depends mainly upon the ADA and SAGA histone acetyltransferase complexes for which Gcn5 is the catalytic subunit. Previous screens have determined that global acetylation is reduced in cells lac...

Descripción completa

Detalles Bibliográficos
Autores principales: Kassem, Sari, Villanyi, Zoltan, Collart, Martine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388395/
https://www.ncbi.nlm.nih.gov/pubmed/28180299
http://dx.doi.org/10.1093/nar/gkw1059