Single cell transcriptomics reveals unanticipated features of early hematopoietic precursors

Molecular changes underlying stem cell differentiation are of fundamental interest. scRNA-seq on murine hematopoietic stem cells (HSC) and their progeny MPP1 separated the cells into 3 main clusters with distinct features: active, quiescent, and an un-characterized cluster. Induction of anemia resul...

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Detalles Bibliográficos
Autores principales: Yang, Jennifer, Tanaka, Yoshiaki, Seay, Montrell, Li, Zhen, Jin, Jiaqi, Garmire, Lana Xia, Zhu, Xun, Taylor, Ashley, Li, Weidong, Euskirchen, Ghia, Halene, Stephanie, Kluger, Yuval, Snyder, Michael P., Park, In-Hyun, Pan, Xinghua, Weissman, Sherman Morton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388401/
https://www.ncbi.nlm.nih.gov/pubmed/28003475
http://dx.doi.org/10.1093/nar/gkw1214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388401/
https://www.ncbi.nlm.nih.gov/pubmed/28003475
http://dx.doi.org/10.1093/nar/gkw1214

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