DNA microstructure influences selective binding of small molecules designed to target mixed-site DNA sequences

Specific targeting of protein–nucleic acid interactions is an area of current interest, for example, in the regulation of gene-expression. Most transcription factor proteins bind in the DNA major groove; however, we are interested in an approach using small molecules to target the minor groove to co...

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Detalles Bibliográficos
Autores principales: Laughlin-Toth, Sarah, Carter, E. Kathleen, Ivanov, Ivaylo, Wilson, W. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388402/
https://www.ncbi.nlm.nih.gov/pubmed/28180310
http://dx.doi.org/10.1093/nar/gkw1232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388402/
https://www.ncbi.nlm.nih.gov/pubmed/28180310
http://dx.doi.org/10.1093/nar/gkw1232

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