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DNA microstructure influences selective binding of small molecules designed to target mixed-site DNA sequences
Specific targeting of protein–nucleic acid interactions is an area of current interest, for example, in the regulation of gene-expression. Most transcription factor proteins bind in the DNA major groove; however, we are interested in an approach using small molecules to target the minor groove to co...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388402/ https://www.ncbi.nlm.nih.gov/pubmed/28180310 http://dx.doi.org/10.1093/nar/gkw1232 |