Structure based comprehensive modelling, spatial fingerprints mapping and ADME screening of curcumin analogues as novel ALR2 inhibitors

Aldose reductase (ALR2) inhibition is the most legitimate approach for the management of diabetic complications. The limited triumph in the drug development against ALR2 is mainly because of its close structural similarity with the other members of aldo-keto reductase (AKR) superfamily viz. ALR1, AK...

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Detalles Bibliográficos
Autores principales: Verma, Sant Kumar, Thareja, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388491/
https://www.ncbi.nlm.nih.gov/pubmed/28399135
http://dx.doi.org/10.1371/journal.pone.0175318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388491/
https://www.ncbi.nlm.nih.gov/pubmed/28399135
http://dx.doi.org/10.1371/journal.pone.0175318

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