p27(Kip1) promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway

p27(Kip1) (p27) is a cyclin-CDK inhibitor and negative regulator of cell proliferation. p27 also controls other cellular processes including migration and cytoplasmic p27 can act as an oncogene. Furthermore, cytoplasmic p27 promotes invasion and metastasis, in part by promoting epithelial to mesench...

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Detalles Bibliográficos
Autores principales: Jeannot, Pauline, Nowosad, Ada, Perchey, Renaud T, Callot, Caroline, Bennana, Evangeline, Katsube, Takanori, Mayeux, Patrick, Guillonneau, François, Manenti, Stéphane, Besson, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388532/
https://www.ncbi.nlm.nih.gov/pubmed/28287395
http://dx.doi.org/10.7554/eLife.22207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388532/
https://www.ncbi.nlm.nih.gov/pubmed/28287395
http://dx.doi.org/10.7554/eLife.22207

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