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Engineering of a synthetic quadrastable gene network to approach Waddington landscape and cell fate determination
The process of cell fate determination has been depicted intuitively as cells travelling and resting on a rugged landscape, which has been probed by various theoretical studies. However, few studies have experimentally demonstrated how underlying gene regulatory networks shape the landscape and henc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388541/ https://www.ncbi.nlm.nih.gov/pubmed/28397688 http://dx.doi.org/10.7554/eLife.23702 |