cAMP Signaling in Brain is Decreased in Unmedicated Depressed Patients and Increased by Treatment with a Selective Serotonin Reuptake Inhibitor

Basic studies exploring the importance of the cyclic adenosine monophosphate (cAMP) cascade in major depressive disorder (MDD) have noted that the cAMP cascade is downregulated in MDD and upregulated by antidepressant treatment. We investigated cAMP cascade activity by using (11)C-(R)-rolipram to im...

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Detalles Bibliográficos
Autores principales: Fujita, Masahiro, Richards, Erica M., Niciu, Mark J., Ionescu, Dawn F., Zoghbi, Sami S., Hong, Jinsoo, Telu, Sanjay, Hines, Christina S., Pike, Victor W., Zarate, Carlos A., Innis, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388600/
https://www.ncbi.nlm.nih.gov/pubmed/27725657
http://dx.doi.org/10.1038/mp.2016.171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388600/
https://www.ncbi.nlm.nih.gov/pubmed/27725657
http://dx.doi.org/10.1038/mp.2016.171

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