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Scalable Downstream Strategies for Purification of Recombinant Adeno-Associated Virus Vectors in Light of the Properties

Recombinant adeno-associated virus (rAAV) vector is one of the promising delivery tools for gene therapy. Currently, hundreds of clinical trials are performed but the major barrier for clinical application is the absence of any ideal large scale production technique to obtain sufficient and highly p...

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Detalles Bibliográficos
Autores principales: Qu, Weihong, Wang, Mingxi, Wu, Yaqing, Xu, Ruian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388796/
https://www.ncbi.nlm.nih.gov/pubmed/25941887
http://dx.doi.org/10.2174/1389201016666150505122228