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Control of gdhR Expression in Neisseria gonorrhoeae via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pump Operon

The MtrCDE efflux pump of Neisseria gonorrhoeae contributes to gonococcal resistance to a number of antibiotics used previously or currently in treatment of gonorrhea, as well as to host-derived antimicrobials that participate in innate defense. Overexpression of the MtrCDE efflux pump increases gon...

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Detalles Bibliográficos
Autores principales: Rouquette-Loughlin, Corinne E., Zalucki, Yaramah M., Dhulipala, Vijaya L., Balthazar, Jacqueline T., Doyle, Raúl G., Nicholas, Robert A., Begum, Afrin A., Raterman, Erica L., Jerse, Ann E., Shafer, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388806/
https://www.ncbi.nlm.nih.gov/pubmed/28400529
http://dx.doi.org/10.1128/mBio.00449-17