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Apoptosis Signal-regulating Kinase 1 promotes Ochratoxin A-induced renal cytotoxicity

Oxidative stress and apoptosis are involved in Ochratoxin A (OTA)-induced renal cytotoxicity. Apoptosis signal-regulating kinase 1 (ASK1) is a Mitogen-Activated Protein Kinase Kinase Kinase (MAPKKK, MAP3K) family member that plays an important role in oxidative stress-induced cell apoptosis. In this...

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Detalles Bibliográficos
Autores principales: Liang, Rui, Shen, Xiao Li, Zhang, Boyang, Li, Yuzhe, Xu, Wentao, Zhao, Changhui, Luo, YunBo, Huang, Kunlun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389036/
https://www.ncbi.nlm.nih.gov/pubmed/25627963
http://dx.doi.org/10.1038/srep08078