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Apoptosis Signal-regulating Kinase 1 promotes Ochratoxin A-induced renal cytotoxicity
Oxidative stress and apoptosis are involved in Ochratoxin A (OTA)-induced renal cytotoxicity. Apoptosis signal-regulating kinase 1 (ASK1) is a Mitogen-Activated Protein Kinase Kinase Kinase (MAPKKK, MAP3K) family member that plays an important role in oxidative stress-induced cell apoptosis. In this...
Autores principales: | Liang, Rui, Shen, Xiao Li, Zhang, Boyang, Li, Yuzhe, Xu, Wentao, Zhao, Changhui, Luo, YunBo, Huang, Kunlun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389036/ https://www.ncbi.nlm.nih.gov/pubmed/25627963 http://dx.doi.org/10.1038/srep08078 |
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