Differential mechanisms of asparaginase resistance in B-type acute lymphoblastic leukemia and malignant natural killer cell lines

Bacterial L-asparaginase (ASNase), hydrolyzing L-asparagine (Asn), is an important drug for treating patients with acute lymphoblastic leukaemia (ALL) and natural killer (NK) cell lymphoma. Although different native or pegylated ASNase-based chemotherapy are efficient, disease relapse is frequently...

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Detalles Bibliográficos
Autores principales: Chien, Wei-Wen, Le Beux, Céline, Rachinel, Nicolas, Julien, Michel, Lacroix, Claire-Emmanuelle, Allas, Soraya, Sahakian, Pierre, Cornut-Thibaut, Aurélie, Lionnard, Loïc, Kucharczak, Jérôme, Aouacheria, Abdel, Abribat, Thierry, Salles, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389037/
https://www.ncbi.nlm.nih.gov/pubmed/25626693
http://dx.doi.org/10.1038/srep08068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389037/
https://www.ncbi.nlm.nih.gov/pubmed/25626693
http://dx.doi.org/10.1038/srep08068

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