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Differential mechanisms of asparaginase resistance in B-type acute lymphoblastic leukemia and malignant natural killer cell lines

Bacterial L-asparaginase (ASNase), hydrolyzing L-asparagine (Asn), is an important drug for treating patients with acute lymphoblastic leukaemia (ALL) and natural killer (NK) cell lymphoma. Although different native or pegylated ASNase-based chemotherapy are efficient, disease relapse is frequently...

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Detalles Bibliográficos
Autores principales:	Chien, Wei-Wen, Le Beux, Céline, Rachinel, Nicolas, Julien, Michel, Lacroix, Claire-Emmanuelle, Allas, Soraya, Sahakian, Pierre, Cornut-Thibaut, Aurélie, Lionnard, Loïc, Kucharczak, Jérôme, Aouacheria, Abdel, Abribat, Thierry, Salles, Gilles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389037/ https://www.ncbi.nlm.nih.gov/pubmed/25626693 http://dx.doi.org/10.1038/srep08068

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