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Lipids bearing extruded-spheronized pellets for extended release of poorly soluble antiemetic agent—Meclizine HCl

BACKGROUND: Antiemetic agent Meclizine HCl, widely prescribed in vertigo, is available only in immediate release dosage forms. The approved therapeutic dose and shorter elimination half-life make Meclizine HCl a potential candidate to be formulated in extended release dosage form. This study was aim...

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Detalles Bibliográficos
Autores principales: Qazi, Faaiza, Shoaib, Muhammad Harris, Yousuf, Rabia Ismail, Nasiri, Muhammad Iqbal, Ahmed, Kamran, Ahmad, Mansoor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389104/
https://www.ncbi.nlm.nih.gov/pubmed/28403892
http://dx.doi.org/10.1186/s12944-017-0466-x