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Lipids bearing extruded-spheronized pellets for extended release of poorly soluble antiemetic agent—Meclizine HCl
BACKGROUND: Antiemetic agent Meclizine HCl, widely prescribed in vertigo, is available only in immediate release dosage forms. The approved therapeutic dose and shorter elimination half-life make Meclizine HCl a potential candidate to be formulated in extended release dosage form. This study was aim...
Autores principales: | Qazi, Faaiza, Shoaib, Muhammad Harris, Yousuf, Rabia Ismail, Nasiri, Muhammad Iqbal, Ahmed, Kamran, Ahmad, Mansoor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389104/ https://www.ncbi.nlm.nih.gov/pubmed/28403892 http://dx.doi.org/10.1186/s12944-017-0466-x |
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