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Empirical Bayes method for reducing false discovery rates of correlation matrices with block diagonal structure

BACKGROUND: Correlation matrices are important in inferring relationships and networks between regulatory or signalling elements in biological systems. With currently available technology sample sizes for experiments are typically small, meaning that these correlations can be difficult to estimate....

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Detalles Bibliográficos
Autores principales: Pacini, Clare, Ajioka, James W., Micklem, Gos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389176/
https://www.ncbi.nlm.nih.gov/pubmed/28403823
http://dx.doi.org/10.1186/s12859-017-1623-y