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Multi-tissue DNA methylation age predictor in mouse

BACKGROUND: DNA methylation changes at a discrete set of sites in the human genome are predictive of chronological and biological age. However, it is not known whether these changes are causative or a consequence of an underlying ageing process. It has also not been shown whether this epigenetic clo...

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Detalles Bibliográficos
Autores principales: Stubbs, Thomas M., Bonder, Marc Jan, Stark, Anne-Katrien, Krueger, Felix, von Meyenn, Ferdinand, Stegle, Oliver, Reik, Wolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389178/
https://www.ncbi.nlm.nih.gov/pubmed/28399939
http://dx.doi.org/10.1186/s13059-017-1203-5