Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients

BACKGROUND: Breast carcinogenesis is a multistep process involving genetic and epigenetic changes. Tumor tissues are frequently characterized by gene-specific hypermethylation and global DNA hypomethylation. Aberrant DNA methylation levels have, however, not only been found in tumors, but also in tu...

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Detalles Bibliográficos
Autores principales: Spitzwieser, Melanie, Entfellner, Elisabeth, Werner, Bettina, Pulverer, Walter, Pfeiler, Georg, Hacker, Stefan, Cichna-Markl, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389179/
https://www.ncbi.nlm.nih.gov/pubmed/28403857
http://dx.doi.org/10.1186/s12885-017-3244-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389179/
https://www.ncbi.nlm.nih.gov/pubmed/28403857
http://dx.doi.org/10.1186/s12885-017-3244-2

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