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Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients
BACKGROUND: Breast carcinogenesis is a multistep process involving genetic and epigenetic changes. Tumor tissues are frequently characterized by gene-specific hypermethylation and global DNA hypomethylation. Aberrant DNA methylation levels have, however, not only been found in tumors, but also in tu...
Autores principales: | Spitzwieser, Melanie, Entfellner, Elisabeth, Werner, Bettina, Pulverer, Walter, Pfeiler, Georg, Hacker, Stefan, Cichna-Markl, Margit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389179/ https://www.ncbi.nlm.nih.gov/pubmed/28403857 http://dx.doi.org/10.1186/s12885-017-3244-2 |
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