Intranasal immunization of pigs with porcine reproductive and respiratory syndrome virus-like particles plus 2′, 3′-cGAMP VacciGrade™ adjuvant exacerbates viremia after virus challenge

BACKGROUND: Porcine reproductive and respiratory syndrome virus (PRRSV) causes reproductive failure in pregnant sows and acute respiratory disease in young pigs. It is a leading infectious agent of swine respiratory complex, which has significant negative economic impact on the swine industry. Comme...

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Detalles Bibliográficos
Autores principales: Van Noort, Alexandria, Nelsen, April, Pillatzki, Angela E., Diel, Diego G., Li, Feng, Nelson, Eric, Wang, Xiuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389191/
https://www.ncbi.nlm.nih.gov/pubmed/28403874
http://dx.doi.org/10.1186/s12985-017-0746-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389191/
https://www.ncbi.nlm.nih.gov/pubmed/28403874
http://dx.doi.org/10.1186/s12985-017-0746-0

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