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Complement C5a receptor knockout has diminished light-induced microglia/macrophage retinal migration

PURPOSE: The complement system is involved in the pathogenesis of age-related macular degeneration (AMD). Because activated microglia are also associated with AMD, we studied the relationship between complement anaphylatoxin receptors and microglial recruitment. METHODS: We assessed the effect of an...

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Detalles Bibliográficos
Autores principales: Song, Delu, Sulewski, Michael E., Wang, Chenguang, Song, Jiantao, Bhuyan, Rupak, Sterling, Jacob, Clark, Esther, Song, Wen-Chao, Dunaief, Joshua L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389337/
https://www.ncbi.nlm.nih.gov/pubmed/28442885