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Bone Marrow Adipose Tissue Deficiency Increases Disuse-Induced Bone Loss in Male Mice

Bone marrow adipose tissue (MAT) is negatively associated with bone mass. Since osteoblasts and adipocytes are derived from the same precursor cells, adipocyte differentiation may occur at the expense of osteoblast differentiation. We used MAT-deficient Kit(W/W−v) (MAT-) mice to determine if absence...

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Detalles Bibliográficos
Autores principales: Keune, Jessica A., Wong, Carmen P., Branscum, Adam J., Iwaniec, Urszula T., Turner, Russell T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389344/
https://www.ncbi.nlm.nih.gov/pubmed/28402337
http://dx.doi.org/10.1038/srep46325