Spliceosomal protein eftud2 mutation leads to p53-dependent apoptosis in zebrafish neural progenitors

Haploinsufficiency of EFTUD2 (Elongation Factor Tu GTP Binding Domain Containing 2) is linked to human mandibulofacial dysostosis, Guion-Almeida type (MFDGA), but the underlying cellular and molecular mechanisms remain to be addressed. We report here the isolation, cloning and functional analysis of...

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Detalles Bibliográficos
Autores principales: Lei, Lei, Yan, Shou-Yu, Yang, Ran, Chen, Jia-Yu, Li, Yumei, Bu, Ye, Chang, Nannan, Zhou, Qinchao, Zhu, Xiaojun, Li, Chuan-Yun, Xiong, Jing-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389467/
https://www.ncbi.nlm.nih.gov/pubmed/27899647
http://dx.doi.org/10.1093/nar/gkw1043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389467/
https://www.ncbi.nlm.nih.gov/pubmed/27899647
http://dx.doi.org/10.1093/nar/gkw1043

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