DNA polymerase β contains a functional nuclear localization signal at its N-terminus

DNA polymerase β (pol β) requires nuclear localization to fulfil its DNA repair function. Although its small size has been interpreted to imply the absence of a need for active nuclear import, sequence and structural analysis suggests that a monopartite nuclear localization signal (NLS) may reside i...

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Detalles Bibliográficos
Autores principales: Kirby, Thomas W., Gassman, Natalie R., Smith, Cassandra E., Zhao, Ming-Lang, Horton, Julie K., Wilson, Samuel H., London, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389473/
https://www.ncbi.nlm.nih.gov/pubmed/27956495
http://dx.doi.org/10.1093/nar/gkw1257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389473/
https://www.ncbi.nlm.nih.gov/pubmed/27956495
http://dx.doi.org/10.1093/nar/gkw1257

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