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DNA polymerase β contains a functional nuclear localization signal at its N-terminus
DNA polymerase β (pol β) requires nuclear localization to fulfil its DNA repair function. Although its small size has been interpreted to imply the absence of a need for active nuclear import, sequence and structural analysis suggests that a monopartite nuclear localization signal (NLS) may reside i...
Autores principales: | Kirby, Thomas W., Gassman, Natalie R., Smith, Cassandra E., Zhao, Ming-Lang, Horton, Julie K., Wilson, Samuel H., London, Robert E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389473/ https://www.ncbi.nlm.nih.gov/pubmed/27956495 http://dx.doi.org/10.1093/nar/gkw1257 |
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