DNA binding specificities of Escherichia coli Cas1–Cas2 integrase drive its recruitment at the CRISPR locus

Prokaryotic adaptive immunity relies on the capture of fragments of invader DNA (protospacers) followed by their recombination at a dedicated acceptor DNA locus. This integrative mechanism, called adaptation, needs both Cas1 and Cas2 proteins. Here, we studied in vitro the binding of an Escherichia...

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Detalles Bibliográficos
Autores principales: Moch, Clara, Fromant, Michel, Blanquet, Sylvain, Plateau, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389526/
https://www.ncbi.nlm.nih.gov/pubmed/28034956
http://dx.doi.org/10.1093/nar/gkw1309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389526/
https://www.ncbi.nlm.nih.gov/pubmed/28034956
http://dx.doi.org/10.1093/nar/gkw1309

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