Different enhancer classes in Drosophila bind distinct architectural proteins and mediate unique chromatin interactions and 3D architecture

Eukaryotic gene expression is regulated by enhancer–promoter interactions but the molecular mechanisms that govern specificity have remained elusive. Genome-wide studies utilizing STARR-seq identified two enhancer classes in Drosophila that interact with different core promoters: housekeeping enhanc...

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Detalles Bibliográficos
Autores principales: Cubeñas-Potts, Caelin, Rowley, M. Jordan, Lyu, Xiaowen, Li, Ge, Lei, Elissa P., Corces, Victor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389536/
https://www.ncbi.nlm.nih.gov/pubmed/27899590
http://dx.doi.org/10.1093/nar/gkw1114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389536/
https://www.ncbi.nlm.nih.gov/pubmed/27899590
http://dx.doi.org/10.1093/nar/gkw1114

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