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Different enhancer classes in Drosophila bind distinct architectural proteins and mediate unique chromatin interactions and 3D architecture
Eukaryotic gene expression is regulated by enhancer–promoter interactions but the molecular mechanisms that govern specificity have remained elusive. Genome-wide studies utilizing STARR-seq identified two enhancer classes in Drosophila that interact with different core promoters: housekeeping enhanc...
Autores principales: | Cubeñas-Potts, Caelin, Rowley, M. Jordan, Lyu, Xiaowen, Li, Ge, Lei, Elissa P., Corces, Victor G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389536/ https://www.ncbi.nlm.nih.gov/pubmed/27899590 http://dx.doi.org/10.1093/nar/gkw1114 |
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