Topoisomerase 3β is the major topoisomerase for mRNAs and linked to neurodevelopment and mental dysfunction

Human cells contain five topoisomerases in the nucleus and cytoplasm, but which one is the major topoisomerase for mRNAs is unclear. To date, Top3β is the only known topoisomerase that possesses RNA topoisomerase activity, binds mRNA translation machinery and interacts with an RNA-binding protein, F...

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Detalles Bibliográficos
Autores principales: Ahmad, Muzammil, Shen, Weiping, Li, Wen, Xue, Yutong, Zou, Sige, Xu, Dongyi, Wang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389537/
https://www.ncbi.nlm.nih.gov/pubmed/28039324
http://dx.doi.org/10.1093/nar/gkw1293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389537/
https://www.ncbi.nlm.nih.gov/pubmed/28039324
http://dx.doi.org/10.1093/nar/gkw1293

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