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Topoisomerase 3β is the major topoisomerase for mRNAs and linked to neurodevelopment and mental dysfunction
Human cells contain five topoisomerases in the nucleus and cytoplasm, but which one is the major topoisomerase for mRNAs is unclear. To date, Top3β is the only known topoisomerase that possesses RNA topoisomerase activity, binds mRNA translation machinery and interacts with an RNA-binding protein, F...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389537/ https://www.ncbi.nlm.nih.gov/pubmed/28039324 http://dx.doi.org/10.1093/nar/gkw1293 |