SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription

SIRT7 is an NAD(+)-dependent protein deacetylase that regulates cell growth and proliferation. Previous studies have shown that SIRT7 is required for RNA polymerase I (Pol I) transcription and pre-rRNA processing. Here, we took a proteomic approach to identify novel molecular targets and characteriz...

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Detalles Bibliográficos
Autores principales: Blank, Maximilian F., Chen, Sifan, Poetz, Fabian, Schnölzer, Martina, Voit, Renate, Grummt, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389538/
https://www.ncbi.nlm.nih.gov/pubmed/28426094
http://dx.doi.org/10.1093/nar/gkx053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389538/
https://www.ncbi.nlm.nih.gov/pubmed/28426094
http://dx.doi.org/10.1093/nar/gkx053

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