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A genome-integrated massively parallel reporter assay reveals DNA sequence determinants of cis-regulatory activity in neural cells

Recent large-scale genomics efforts to characterize the cis-regulatory sequences that orchestrate genome-wide expression patterns have produced impressive catalogues of putative regulatory elements. Most of these sequences have not been functionally tested, and our limited understanding of the non-c...

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Detalles Bibliográficos
Autores principales: Maricque, Brett B., Dougherty, Joseph D., Cohen, Barak A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389540/
https://www.ncbi.nlm.nih.gov/pubmed/28204611
http://dx.doi.org/10.1093/nar/gkw942