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miRTar2GO: a novel rule-based model learning method for cell line specific microRNA target prediction that integrates Ago2 CLIP-Seq and validated microRNA–target interaction data

MicroRNAs (miRNAs) are ∼19–22 nucleotides (nt) long regulatory RNAs that regulate gene expression by recognizing and binding to complementary sequences on mRNAs. The key step in revealing the function of a miRNA, is the identification of miRNA target genes. Recent biochemical advances including PAR-...

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Detalles Bibliográficos
Autores principales: Ahadi, Alireza, Sablok, Gaurav, Hutvagner, Gyorgy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389546/
https://www.ncbi.nlm.nih.gov/pubmed/27903911
http://dx.doi.org/10.1093/nar/gkw1185