Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts

The dynamic interaction of DNA methylation and transcription factor binding in regulating spatiotemporal gene expression is essential for embryogenesis, but the underlying mechanisms remain understudied. In this study, using mouse models and integration of in vitro and in vivo genetic and epigenetic...

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Detalles Bibliográficos
Autores principales: Zhang, Donghong, Wu, Bingruo, Wang, Ping, Wang, Yidong, Lu, Pengfei, Nechiporuk, Tamilla, Floss, Thomas, Greally, John M., Zheng, Deyou, Zhou, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389556/
https://www.ncbi.nlm.nih.gov/pubmed/27956497
http://dx.doi.org/10.1093/nar/gkw1258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389556/
https://www.ncbi.nlm.nih.gov/pubmed/27956497
http://dx.doi.org/10.1093/nar/gkw1258

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