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Molecular determinants for CRISPR RNA maturation in the Cas10–Csm complex and roles for non-Cas nucleases

CRISPR–Cas (Clustered regularly interspaced short palindromic repeats-CRISPR-associated proteins) is a prokaryotic immune system that destroys foreign nucleic acids in a sequence-specific manner using Cas nucleases guided by short RNAs (crRNAs). Staphylococcus epidermidis harbours a Type III-A CRISP...

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Detalles Bibliográficos
Autores principales: Walker, Forrest C., Chou-Zheng, Lucy, Dunkle, Jack A., Hatoum-Aslan, Asma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389561/
https://www.ncbi.nlm.nih.gov/pubmed/28204542
http://dx.doi.org/10.1093/nar/gkw891