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Core binding factor (CBF) is required for Epstein-Barr virus EBNA3 proteins to regulate target gene expression

ChIP-seq performed on lymphoblastoid cell lines (LCLs), expressing epitope-tagged EBNA3A, EBNA3B or EBNA3C from EBV-recombinants, revealed important principles of EBNA3 binding to chromatin. When combined with global chromatin looping data, EBNA3-bound loci were found to have a singular character, e...

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Detalles Bibliográficos
Autores principales: Paschos, Kostas, Bazot, Quentin, Ho, Guiyi, Parker, Gillian A., Lees, Jonathan, Barton, Geraint, Allday, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389572/
https://www.ncbi.nlm.nih.gov/pubmed/27903901
http://dx.doi.org/10.1093/nar/gkw1167