Engineering antibody-like inhibitors to prevent and treat HIV-1 infection

PURPOSE OF REVIEW: Here we discuss recently developed HIV-1 entry inhibitors that can target multiple epitopes on the HIV-1 envelope glycoprotein (Env), with an emphasis on eCD4-Ig. Some of these inhibitors are more potent and broader than any single antibody characterized to date. We also discuss t...

Descripción completa

Detalles Bibliográficos
Autores principales: Gardner, Matthew R., Farzan, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
HIV AND NOVEL STRATEGIES FOR INDUCTION OF BROAD NEUTRALIZING ANTIBODIES FOLLOWING VACCINATION: Edited by Ralf Wagner
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389584/
https://www.ncbi.nlm.nih.gov/pubmed/28422793
http://dx.doi.org/10.1097/COH.0000000000000367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389584/
https://www.ncbi.nlm.nih.gov/pubmed/28422793
http://dx.doi.org/10.1097/COH.0000000000000367

Ejemplares similares