Methylation-sensitive enrichment of minor DNA alleles using a double-strand DNA-specific nuclease

Aberrant methylation changes, often present in a minor allelic fraction in clinical samples such as plasma-circulating DNA (cfDNA), are potentially powerful prognostic and predictive biomarkers in human disease including cancer. We report on a novel, highly-multiplexed approach to facilitate analysi...

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Detalles Bibliográficos
Autores principales: Liu, Yibin, Song, Chen, Ladas, Ioannis, Fitarelli-Kiehl, Mariana, Makrigiorgos, G. Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389605/
https://www.ncbi.nlm.nih.gov/pubmed/27903892
http://dx.doi.org/10.1093/nar/gkw1166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389605/
https://www.ncbi.nlm.nih.gov/pubmed/27903892
http://dx.doi.org/10.1093/nar/gkw1166

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