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Rad6–Bre1-mediated H2B ubiquitination regulates telomere replication by promoting telomere-end resection

Rad6 and Bre1, ubiquitin-conjugating E2 and E3 enzymes respectively, are responsible for histone H2B lysine 123 mono-ubiquitination (H2Bub1) in Saccharomyces cerevisiae. Previous studies have shown that Rad6 and Bre1 regulate telomere length and recombination. However, the underlying molecular mecha...

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Detalles Bibliográficos
Autores principales: Wu, Zhenfang, Liu, Jun, Zhang, Qiong-Di, Lv, De-Kang, Wu, Nian-Feng, Zhou, Jin-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389628/
https://www.ncbi.nlm.nih.gov/pubmed/28180293
http://dx.doi.org/10.1093/nar/gkx101