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Binding of interferon reduces the force of unfolding for interferon receptor 1

Differential signaling of the type I interferon receptor (IFNAR) has been correlated with the ability of its subunit, IFNAR1, to differentially recognize a large spectrum of different ligands, which involves intricate conformational re-arrangements of multiple interacting domains. To shed light onto...

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Detalles Bibliográficos
Autores principales: Chuartzman, Silvia G., Nevo, Reinat, Waichman, Sharon, Shental, Dalit, Piehler, Jacob, Levy, Yaakov, Reich, Ziv, Kapon, Ruti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389645/
https://www.ncbi.nlm.nih.gov/pubmed/28403186
http://dx.doi.org/10.1371/journal.pone.0175413