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Structural analysis reveals the flexible C-terminus of Nop15 undergoes rearrangement to recognize a pre-ribosomal RNA folding intermediate

The RNA recognition motif (RRM) is the most abundant RNA-binding domain in eukaryotes, and it plays versatile roles in RNA metabolism. Despite its abundance, diversity of RRM structure and function is generated by variations on a conserved core. Yeast Nop15 is an RRM protein that is essential for la...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Gonzalez, Lauren E., Hall, Traci M. Tanaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389651/
https://www.ncbi.nlm.nih.gov/pubmed/27789691
http://dx.doi.org/10.1093/nar/gkw961