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QSEA—modelling of genome-wide DNA methylation from sequencing enrichment experiments

Genome-wide enrichment of methylated DNA followed by sequencing (MeDIP-seq) offers a reasonable compromise between experimental costs and genomic coverage. However, the computational analysis of these experiments is complex, and quantification of the enrichment signals in terms of absolute levels of...

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Detalles Bibliográficos
Autores principales: Lienhard, Matthias, Grasse, Sabrina, Rolff, Jana, Frese, Steffen, Schirmer, Uwe, Becker, Michael, Börno, Stefan, Timmermann, Bernd, Chavez, Lukas, Sültmann, Holger, Leschber, Gunda, Fichtner, Iduna, Schweiger, Michal R, Herwig, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389680/
https://www.ncbi.nlm.nih.gov/pubmed/27913729
http://dx.doi.org/10.1093/nar/gkw1193