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QSEA—modelling of genome-wide DNA methylation from sequencing enrichment experiments
Genome-wide enrichment of methylated DNA followed by sequencing (MeDIP-seq) offers a reasonable compromise between experimental costs and genomic coverage. However, the computational analysis of these experiments is complex, and quantification of the enrichment signals in terms of absolute levels of...
Autores principales: | Lienhard, Matthias, Grasse, Sabrina, Rolff, Jana, Frese, Steffen, Schirmer, Uwe, Becker, Michael, Börno, Stefan, Timmermann, Bernd, Chavez, Lukas, Sültmann, Holger, Leschber, Gunda, Fichtner, Iduna, Schweiger, Michal R, Herwig, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389680/ https://www.ncbi.nlm.nih.gov/pubmed/27913729 http://dx.doi.org/10.1093/nar/gkw1193 |
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