sCNAphase: using haplotype resolved read depth to genotype somatic copy number alterations from low cellularity aneuploid tumors

Accurate identification of copy number alterations is an essential step in understanding the events driving tumor progression. While a variety of algorithms have been developed to use high-throughput sequencing data to profile copy number changes, no tool is able to reliably characterize ploidy and...

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Detalles Bibliográficos
Autores principales: Chen, Wenhan, Robertson, Alan J., Ganesamoorthy, Devika, Coin, Lachlan J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389684/
https://www.ncbi.nlm.nih.gov/pubmed/27903916
http://dx.doi.org/10.1093/nar/gkw1086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389684/
https://www.ncbi.nlm.nih.gov/pubmed/27903916
http://dx.doi.org/10.1093/nar/gkw1086

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