Identification of a novel K311 ubiquitination site critical for androgen receptor transcriptional activity

The androgen receptor (AR) is the main driver of prostate cancer (PC) development and progression, and the primary therapeutic target in PC. To date, two functional ubiquitination sites have been identified on AR, both located in its C-terminal ligand binding domain (LBD). Recent reports highlight t...

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Detalles Bibliográficos
Autores principales: McClurg, Urszula L., Cork, David M.W., Darby, Steven, Ryan-Munden, Claudia A., Nakjang, Sirintra, Mendes Côrtes, Leticia, Treumann, Achim, Gaughan, Luke, Robson, Craig N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389688/
https://www.ncbi.nlm.nih.gov/pubmed/27903893
http://dx.doi.org/10.1093/nar/gkw1162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389688/
https://www.ncbi.nlm.nih.gov/pubmed/27903893
http://dx.doi.org/10.1093/nar/gkw1162

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