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Non-canonical targets destabilize microRNAs in human Argonautes

Although much is known about microRNA (miRNA) biogenesis and the mechanism by which miRNAs regulate their targets, little is known about the regulation of miRNA stability. Mature miRNAs are stabilized by binding to Argonaute (Ago) proteins, the core components of the RNA-induced silencing complex (R...

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Detalles Bibliográficos
Autores principales: Park, June Hyun, Shin, Sang-Yoon, Shin, Chanseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389725/
https://www.ncbi.nlm.nih.gov/pubmed/28119422
http://dx.doi.org/10.1093/nar/gkx029