Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation

Genome-wide association studies identified numerous disease risk loci. Delineating molecular mechanisms influenced by cis-regulatory variants is essential to understand gene regulation and ultimately disease pathophysiology. Combining bioinformatics and public domain chromatin information with quant...

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Detalles Bibliográficos
Autores principales: Lee, Heekyoung, Qian, Kun, von Toerne, Christine, Hoerburger, Lena, Claussnitzer, Melina, Hoffmann, Christoph, Glunk, Viktoria, Wahl, Simone, Breier, Michaela, Eck, Franziska, Jafari, Leili, Molnos, Sophie, Grallert, Harald, Dahlman, Ingrid, Arner, Peter, Brunner, Cornelia, Hauner, Hans, Hauck, Stefanie M., Laumen, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389726/
https://www.ncbi.nlm.nih.gov/pubmed/28334807
http://dx.doi.org/10.1093/nar/gkx105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389726/
https://www.ncbi.nlm.nih.gov/pubmed/28334807
http://dx.doi.org/10.1093/nar/gkx105

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