Cargando…
Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation
Genome-wide association studies identified numerous disease risk loci. Delineating molecular mechanisms influenced by cis-regulatory variants is essential to understand gene regulation and ultimately disease pathophysiology. Combining bioinformatics and public domain chromatin information with quant...
Autores principales: | Lee, Heekyoung, Qian, Kun, von Toerne, Christine, Hoerburger, Lena, Claussnitzer, Melina, Hoffmann, Christoph, Glunk, Viktoria, Wahl, Simone, Breier, Michaela, Eck, Franziska, Jafari, Leili, Molnos, Sophie, Grallert, Harald, Dahlman, Ingrid, Arner, Peter, Brunner, Cornelia, Hauner, Hans, Hauck, Stefanie M., Laumen, Helmut |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389726/ https://www.ncbi.nlm.nih.gov/pubmed/28334807 http://dx.doi.org/10.1093/nar/gkx105 |
Ejemplares similares
-
Effects of Genetic Loci Associated with Central Obesity on Adipocyte Lipolysis
por: Strawbridge, Rona J., et al.
Publicado: (2016) -
Dynamic modelling of an ACADS genotype in fatty acid oxidation – Application of cellular models for the analysis of common genetic variants
por: Matejka, Kerstin, et al.
Publicado: (2019) -
Plasma Metabolomics Reveal Alterations of Sphingo- and Glycerophospholipid Levels in Non-Diabetic Carriers of the Transcription Factor 7-Like 2 Polymorphism rs7903146
por: Then, Cornelia, et al.
Publicado: (2013) -
The Genetics of PPARG and the Skeleton
por: Ackert-Bicknell, Cheryl, et al.
Publicado: (2006) -
Octamer-dependent transcription in T cells is mediated by NFAT and NF-κB
por: Mueller, Kerstin, et al.
Publicado: (2013)