Homologous recombination in budding yeast expressing the human RAD52 gene reveals a Rad51-independent mechanism of conservative double-strand break repair

RAD52 is a homologous recombination (HR) protein that is conserved from bacteriophage to humans. Simultaneously attenuating expression of both the RAD52 gene, and the HR and tumor suppressor gene, BRCA2, in human cells synergistically reduces HR – indicating that RAD52 and BRCA2 control independent...

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Detalles Bibliográficos
Autores principales: Manthey, Glenn M., Clear, Alissa D., Liddell, Lauren C., Negritto, Maria C., Bailis, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389729/
https://www.ncbi.nlm.nih.gov/pubmed/27923995
http://dx.doi.org/10.1093/nar/gkw1228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389729/
https://www.ncbi.nlm.nih.gov/pubmed/27923995
http://dx.doi.org/10.1093/nar/gkw1228

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